Chemical Name: N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)-2-((1,3-dioxo-2-(2-oxopiperidin-3-yl)isoindolin-4-yl)amino)acetamide
Biological ActivityTL 13-22 is a negative control for TL 13-12 (Cat. No. 6744). Displays no degradation of ALK in cell lines. Highly potent inhibitor of ALK (IC50 = 0.54 nM)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Chemically induced degradation of anaplastic lymphoma kinase (ALK).
Powell et al.
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