TokeOni

Tocris Bioscience | Catalog # 6555

NIR-emission luciferin analog; ideal for deep tissue applications; orally bioavailable and brain penetrant
Tocris Bioscience

Key Product Details

Description

NIR-emission luciferin analog; ideal for deep tissue applications; orally bioavailable and brain penetrant

Alternative Names

AkaLumine HCl
View all Bioluminescent Substrates »

Product Description

TokeOni is a near-infrared red (NIR)-emission luciferin analog. Peak luminescence at 677 nM. ~40-fold brighter than the luciferin-luciferase system in vitro, and 100-1000 times brighter in vivo. Allows non-invasive visualization of single cells deep inside freely moving animals. Ideal for deep tissue applications. Water soluble (<40 mM), orally bioavailable and brain penetrant.

This product is supplied as a hydrochloride salt, the stoichiometry of which is batch dependant. Please refer to the Certificate of Analysis to obtain the batch specific Net Product Content.

Optical Data

TokeOni Dye Spectra
Emission Color Near-IR
λem 677 nm
Application BLI, BTI, Deep Tissue Applications

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Product Specifications for TokeOni

Formula

C16H18N2O2S.xHCl

Storage

Store at -20°C

Purity

≥90% (HPLC)

Chemical Name

(4S)-2-[(1E,3E)-4-[4-(Dimethylamino)phenyl]-1,3-butadien-1-yl]-4,5-dihydro-4-thiazolecarboxylic acid hydrochloride

PubChem ID

124203055

InChI Key

PZCNKVAGZCXXHX-SSRSOBHISA-N

SMILES

CN(C1=CC=C(C=C1)/C=C/C=C/C2=N[C@@H](C(O)=O)CS2)C.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 5mg/ml in water with gentle warming and to 10mg/ml in DMSO

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

Product Documents for TokeOni

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TokeOni

For research use only

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