Tomoxetine hydrochloride

Tocris Bioscience | Catalog # 2011

Potent and selective noradrenalin re-uptake inhibitor
Tocris Bioscience

Key Product Details

Description

Potent and selective noradrenalin re-uptake inhibitor

Alternative Names

Atomoxetine,LY 139603
View all Adrenergic Transporter Inhibitors »

Product Description

Tomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). Displays minimal affinity for a range of other neurotransmitter receptors and transporters (Ki > 1 μM). Antidepressant.

Product Specifications for Tomoxetine hydrochloride

Molecular Weight

291.82

Formula

C17H21NO.HCl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(R)-N-Methyl-γ-(2-methylphenoxy)-benzenepropanamine hydrochloride

CAS Number

82248-59-7

PubChem ID

54840

InChI Key

LUCXVPAZUDVVBT-UNTBIKODSA-N

SMILES

Cl[H].CNCC[C@@H](OC1=C(C)C=CC=C1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 14.59 50 with gentle warming

Preparing Stock Solutions for Tomoxetine hydrochloride

The following data is based on the product molecular weight 291.82.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 6.85 mL 34.27 mL 68.54 mL
2.5 mM 1.37 mL 6.85 mL 13.71 mL
5 mM 0.69 mL 3.43 mL 6.85 mL
25 mM 0.14 mL 0.69 mL 1.37 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 603 publications citing the usage of this product.

Product Documents for Tomoxetine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Tomoxetine hydrochloride

For research use only

Citations for Tomoxetine hydrochloride

Customer Reviews for Tomoxetine hydrochloride (1)

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  • Arrived next day, quality
    Name: Shannon Ballard
    Species: Rat
    Assay Type: In Vivo
    Verified Customer | Posted 07/24/2020
    diluted into saline solution to be injected into animals for observation of behavioral effects

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