Toyocamycin

Tocris Bioscience | Catalog # 5270

Adenosine analog; antifungal antibiotic
Tocris Bioscience

Key Product Details

Description

Adenosine analog; antifungal antibiotic
View all Antibiotics »

Product Description

Toyocamycin is an adenosine analog; antifungal antibiotic. Inhibits RNA self-cleavage in HEK79 cells and PI 3-kinase activity in A431 epidermoid carcinoma cell membrane fractions. Also inhibits thapsigargin-induced XBP1-luciferase activation and induces apoptosis in multiple myeloma cell lines.

Product Specifications for Toyocamycin

Molecular Weight

291.26

Formula

C12H13N5O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

CAS Number

606-58-6

PubChem ID

12444444

InChI Key

XOKJUSAYZUAMGJ-NNXMZFEESA-N

SMILES

NC1=C2C(N([C@@H]3O[C@H](CO)[C@H](O)[C@@H]3O)C=C2C#N)=NC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 29.13 100

Preparing Stock Solutions for Toyocamycin

The following data is based on the product molecular weight 291.26.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.43 mL 17.17 mL 34.33 mL
5 mM 0.69 mL 3.43 mL 6.87 mL
10 mM 0.34 mL 1.72 mL 3.43 mL
50 mM 0.07 mL 0.34 mL 0.69 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Toyocamycin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Toyocamycin

For research use only

Customer Reviews for Toyocamycin (1)

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  • The pathway of inhibition of auxin-responsive gene expression by Toyocamycin was studied
    Name: Josh McKay
    Species: Human
    Verified Customer | Posted 02/18/2019
    The pathway of inhibition of auxin-responsive gene expression by Toyocamycin was studied. Solutions prepared in DMSO can be diluted 20-fold in water.
    Toyocamycin 5270

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