Tracazolate hydrochloride

Key Product Details

Product Description

Tracazolate hydrochloride is a GABA_A receptor modulator. Can potentiate or inhibit recombinant GABA_A function depending on subunit combination. Enhances native GABA_A receptor function and is anxiolytic following systemic administration in vivo.

Product Specifications for Tracazolate hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Tracazolate hydrochloride

The following data is based on the product molecular weight 340.85.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.93 mL	14.67 mL	29.34 mL
5 mM	0.59 mL	2.93 mL	5.87 mL
10 mM	0.29 mL	1.47 mL	2.93 mL
50 mM	0.06 mL	0.29 mL	0.59 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Patel and Malick Pharmacological properties of tracazolate: a new non-benzodiazepine anxiolytic agent. Eur.J.Pharmacol. 1982 PMID: 6121711
• Thompson Tracazolate reveals a novel type of allosteric interaction with recombinant γ-aminobutyric acid_A receptors. Mol.Pharmacol. 2002 PMID: 11901225
• Meiners and Salama Enhancement of benzodiazepine and GABA binding by the novel anxiolytic, tracazolate. Eur.J.Pharmacol. 1982 PMID: 6121710

Product Documents for Tracazolate hydrochloride