U 99194 maleate

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Heterogeneity of behavioural profile between three putative selective D₃ DA receptor antagonists using an ethologically based approach.
   Clifford and Waddington
   Psychopharmacology, 1998;136:284
3. A comparative in vitro and in vivo pharmacological characterization of the novel DA D₃ receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194.
   Audinot et al.
   J.Pharmacol.Exp.Ther., 1998;287:187
4. DA D₁ receptors synergize with D₂, but not D₃ or D₄, receptors in the striatum without the involvement of action potentials.
   LaHoste et al.
   J.Neurosci., 2000;20:6666

Product Datasheets