U0124
Tocris Bioscience | Catalog # 1868
Product Description
U0124 is an inactive analog of U0126 (Cat. No. 1144). Does not inhibit MEK at concentrations up to 100 μM. Used as a negative control.
Active Analog also available.
Product Specifications for U0124
Molecular Weight
Formula
Storage
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 22.63 | 100 |
Preparing Stock Solutions for U0124
The following data is based on the product molecular weight 226.31.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.42 mL | 22.09 mL | 44.19 mL |
| 5 mM | 0.88 mL | 4.42 mL | 8.84 mL |
| 10 mM | 0.44 mL | 2.21 mL | 4.42 mL |
| 50 mM | 0.09 mL | 0.44 mL | 0.88 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.
- Fitzgerald Regulation of voltage-dependent calcium channels in rat sensory neurones involves a Ras-mitogen-activated protein kinase pathway. J.Physiol. 2000 PMID: 10990531
- Sekar Concerted transcriptional activation of the low density lipoprotein receptor gene by Ins and luteinizing hormone in cultured porcine granulosa-luteal cells: possible convergence of protein kinase A, phosphatidylinositol 3-kinase, and mitogen-activated pro Endocrinology 2001 PMID: 11416012
- Favata Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J.Biol.Chem. 1998 PMID: 9660836
Product Documents for U0124
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for U0124
For research use only
Related Research Areas
Citations for U0124
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