UK 14,304

Key Product Details

Product Description

UK 14,304 is a full α₂ adrenergic agonist. Centrally active following systemic administration in vivo.

Water-soluble Salt also available.

Product Specifications for UK 14,304

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for UK 14,304

The following data is based on the product molecular weight 292.14.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.42 mL	17.12 mL	34.23 mL
5 mM	0.68 mL	3.42 mL	6.85 mL
10 mM	0.34 mL	1.71 mL	3.42 mL
50 mM	0.07 mL	0.34 mL	0.68 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 36 publications citing the usage of this product.

• Chopin Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxyDA lesions of the nigrostriatal pathway. J.Pharmacol.Exp.Ther. 1999 PMID: 9918591
• Macdonald Gene targeting - homing in on α₂-adrenoceptor-subtype function. TiPS 1997 PMID: 9227000
• Andorn Specific [³H]UK-14,304 binding in human cortex occurs at multiple high affinity states with α₂-adrenergic selectivity and different affinities for GTP. Life Sci. 1988 PMID: 2904634

Product Documents for UK 14,304