Key Product Details

Species Reactivity

Human

Applications

Western Blot, Blockade of Receptor-ligand Interaction

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Polyclonal Goat IgG
View all ULBP-3 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human ULBP-3
Gly27-Pro216
Accession # NP_078794

Specificity

Detects human ULBP-3 in direct ELISAs and Western blots. In these formats, approximately 5% cross‑reactivity with recombinant human (rh) ULBP-2 is observed and less than 1% cross-reactivity with rhULBP-1 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for ULBP-3 Antibody [FITC]

Application
Recommended Usage

Blockade of Receptor-ligand Interaction

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: ULBP-3

Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. Has lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than doesULBP2 or ULBP1

Long Name

UL16 Binding Protein-3

Alternate Names

ULBP3

Gene Symbol

ULBP3

Additional ULBP-3 Products

Product Documents for ULBP-3 Antibody [FITC]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for ULBP-3 Antibody [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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