UNC 2400

Tocris Bioscience | Catalog # 4905

Negative control of UNC 1999 (Cat. No. 4904)
Tocris Bioscience
Discontinued Product
4905 has been discontinued. View all EZH2 Inhibitor products.

Key Product Details

Description

Negative control of UNC 1999 (Cat. No. 4904)
View all EZH2 Inhibitor »

Product Description

UNC 2400 is a negative control of UNC 1999. Exhibits 1000-fold lower potency than active analog (IC50 values are 62 and >200 μM for EZH1 and EZH2, respectively).

Active Analog also available.

Licensing Information

This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the UNC 1999 probe summary on the SGC website.

Product Specifications for UNC 2400

Molecular Weight

597.79

Formula

C35H47N7O2

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-[(1,2-Dihydro-1,6-dimethyl-2-oxo-4-propyl-3-pyridinyl)methyl]-N-methyl-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxamide

CAS Number

1433200-49-7

PubChem ID

91691116

InChI Key

IFSQHIRDVVFJSQ-UHFFFAOYSA-N

SMILES

CC(C)N1CCN(C2=NC=C(C3=CC(N(C(C)C)N=C4)=C4C(C(N(C)CC5=C(CCC)C=C(C)N(C)C5=O)=O)=C3)C=C2)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 100
DMSO 100

Preparing Stock Solutions for UNC 2400

The following data is based on the product molecular weight 597.79.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.67 mL 8.36 mL 16.73 mL
5 mM 0.33 mL 1.67 mL 3.35 mL
10 mM 0.17 mL 0.84 mL 1.67 mL
50 mM 0.03 mL 0.17 mL 0.33 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 11 publications citing the usage of this product.

Product Documents for UNC 2400

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for UNC 2400

For research use only

Related Research Areas

Cancer Biomarkers
Epigenetics

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