VDAC2/3 Antibody

Novus Biologicals | Catalog # NB100-56463

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Bovine, Canine, Feline, Primate

Cited:

Human

Predicted:

Chicken (92%), Mouse (92%), Rat (92%), Zebrafish (92%). Backed by our 100% Guarantee.

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all VDAC2/3 Primary Antibodies »

Product Specifications

Immunogen

Amino acids 120-132 (KKSGKIKSSYKRE) of human VDAC2 protein were used as the immunogen.

Reactivity Notes

Chimpanzee. 92% sequence identity with Mouse, Rat, Chicken and Zebrafish proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for VDAC2/3 Antibody

Western Blot: VDAC2/3 Antibody [NB100-56463]

Western Blot: VDAC2/3 Antibody [NB100-56463]

Western Blot: VDAC2/3 Antibody [NB100-56463] - analysis of VDAC2/3 in human brain cell lysate in the A) absence and B) presence of immunizing peptide using this antibody. The approximately 55 kD band is not blocked by the immunizing peptide and is believed to result from non-specific cross-reaction.

Applications for VDAC2/3 Antibody

Application
Recommended Usage

Western Blot

1-3 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VDAC2/3

Voltage-dependent anion channels (VDAC) are small pore-forming membrane proteins that regulate metabolite exchange across the mitochondrial outer membrane. Apart from metabolite transfer, VDAC role has also been suggested during apoptosis. VDAC2 is one of the isoforms of VDAC. It interacts with BAK and functions as a specific inhibitor of BAK-dependent mitochondrial apoptosis.

Alternate Names

FLJ23841, hVDAC2, Outer mitochondrial membrane protein porin 2, POR, VDAC-2, voltage-dependent anion channel 2, voltage-dependent anion-selective channel protein 2

Entrez Gene IDs

7417 (Human); 22334 (Mouse); 83531 (Rat)

Gene Symbol

VDAC2

UniProt

P45880 (Human)

Additional VDAC2/3 Products

Product Documents for VDAC2/3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for VDAC2/3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for VDAC2/3 Antibody

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