Vigabatrin

Key Product Details

Product Description

Vigabatrin is a selective GABA-T (transaminase) inhibitor. Anticonvulsant.

Product Specifications for Vigabatrin

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Vigabatrin

The following data is based on the product molecular weight 129.16.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	7.74 mL	38.71 mL	77.42 mL
5 mM	1.55 mL	7.74 mL	15.48 mL
10 mM	0.77 mL	3.87 mL	7.74 mL
50 mM	0.15 mL	0.77 mL	1.55 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 18 publications citing the usage of this product.

• Larsson Differential effect of gamma-vinyl GABA and valproate on GABA transaminase from cultured neurones and astrocytes. Neuropharmacology 1986 PMID: 3092125
• Schmid Vigabatrin modulates benzodiazepine receptor activity in vivo: a positron emission tomography study in baboon. J.Pharmacol.Exp.Ther. 1996 PMID: 8786578
• Halonen Effects of vigab. (γ-vinyl GABA) on neurotransmission-related amino acids and on GABA and benzodiazepine receptor binding in rats. Epilepsia 1991 PMID: 1672276

Product Documents for Vigabatrin