Viomycin

Tocris Bioscience | Catalog # 3787

Antibiotic; inhibits bacterial DNA synthesis
Tocris Bioscience

Key Product Details

Description

Antibiotic; inhibits bacterial DNA synthesis
View all Antibiotics »

Product Description

Viomycin is a member of the tuberactinomycin family of antibiotics. Inhibits group I intron splicing and prokaryotic protein synthesis. Freezes bacterial ribosomes in either the pre- or post-translational state. Facilitates trans-cleavage of the Neurospora VS ribozyme.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications for Viomycin

Molecular Weight

881.85

Formula

C25H43N13O10.2H2SO4

Storage

Store at -20°C

Chemical Name

(S)-3,6-Diamino-N-((3S,9S,12S,15S,Z)3((2R,4S)-6-amino-4-hydroxy-1,2,3,4-tetrahydropyridin-2-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-15-yl)hexanamide disulfate

PubChem ID

90488875

InChI Key

HMKHTQGEDRQEOM-IGZVKJTASA-N

SMILES

O[C@H](N1)C[C@@H]([C@H](C(NC[C@@H](C(N[C@@H](CO)C(N[C@H](C(N2)=O)CO)=O)=O)NC(C[C@@H](N)CCCN)=O)=O)NC(/C2=C/NC(N)=O)=O)NC1=N.OS(O)(=O)=O.OS(O)(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 66.14 75

Preparing Stock Solutions for Viomycin

The following data is based on the product molecular weight 881.85.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 1.51 mL 7.56 mL 15.12 mL
3.75 mM 0.30 mL 1.51 mL 3.02 mL
7.5 mM 0.15 mL 0.76 mL 1.51 mL
37.5 mM 0.03 mL 0.15 mL 0.30 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

Product Documents for Viomycin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Viomycin

For research use only

Customer Reviews for Viomycin (1)

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  • Viomycin and streptomycin were compared in inhibition of bacterial protein production
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 02/13/2019
    Viomycin and streptomycin were compared in inhibition of bacterial protein production.Cross-resistance between streptomycin and other aminoglycosides and polypeptides observed.
    Viomycin 3787

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