WAY 200070

Key Product Details

Product Description

WAY 200070 is a selective ERβ receptor agonist that displays 68-fold selectivity over ERα (EC₅₀ values are 2 and 155 nM for ERβ and ERα respectively). Displays antianxiolytic and antidepressive effects in vivo.

Product Specifications for WAY 200070

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for WAY 200070

The following data is based on the product molecular weight 306.11.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.27 mL	16.33 mL	32.67 mL
5 mM	0.65 mL	3.27 mL	6.53 mL
10 mM	0.33 mL	1.63 mL	3.27 mL
50 mM	0.07 mL	0.33 mL	0.65 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 21 publications citing the usage of this product.

• Hughes WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent. Neuropharmacology 2008 PMID: 18423777
• Clipperton Differential effects of estrogen receptor alpha and beta specific agonists on social learning of food preferences in female mice. Neuropsychopharmacology 2008 PMID: 18004284
• Malamas Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-β ligands. J.Med.Chem. 2004 PMID: 15456246

Product Documents for WAY 200070