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WL 47 - dimer

Catalog #: 5978 Datasheet / COA / SDS

Discontinued Product

5978 has been discontinued.
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WL 47 - dimer
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Description: High affinity caveolin-1 ligand
Product Details
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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

WL 47 - dimer is a high affinity caveolin-1 (CAV1) ligand (Kd = 23 nM); disrupts caveolin-1 oligomers. Exhibits selectivity for CAV1 over BSA, casein and HEWL.

Technical Data

M.Wt:
1844.3
Formula:
C80H130N24O18S4
Sequence:
CSWMRLK CSWMRLK*

(Modifications: Disulfide Bridge = 1-1*)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with kind permission of Professor Gregory Weiss

Background References

  1. Affinity-Guided Design of Caveolin-1 Ligands for Deoligomerization.
    Gilliam et al.
    J.Med.Chem., 2016;59:4019

Product Datasheets

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Reconstitution Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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