WM 3835

Tocris Bioscience | Catalog # 7366

Lysine acetyltransferase HBO1 (KAT7) inhibitor
Tocris Bioscience

Key Product Details

Description

Lysine acetyltransferase HBO1 (KAT7) inhibitor
View all Histone Acetyltransferase Inhibitors »

Product Description

WM 3835 is a lysine acetyltransferase HBO1 (KAT7) inhibitor. Reduces H3K14ac levels and inhibits growth and viability of acute myeloid leukemia cell lines in vitro. Cell-permeable.

Product Specifications for WM 3835

Molecular Weight

400.42

Formula

C20H17FN2O4S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N'-(4-Fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)-3-hydroxybenzenesulfonohydrazide

CAS Number

2229025-70-9

PubChem ID

134581412

InChI Key

KVJFJJXCBRSCDY-UHFFFAOYSA-N

SMILES

CC1=CC(C2=CC=CC=C2)=CC(C(NNS(=O)(C3=CC(O)=CC=C3)=O)=O)=C1F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.04 100
Ethanol 20.02 50

Preparing Stock Solutions for WM 3835

The following data is based on the product molecular weight 400.42.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.50 mL 12.49 mL 24.97 mL
5 mM 0.50 mL 2.50 mL 4.99 mL
10 mM 0.25 mL 1.25 mL 2.50 mL
50 mM 0.05 mL 0.25 mL 0.50 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for WM 3835

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for WM 3835

For research use only

Related Research Areas

Epigenetics

Customer Reviews for WM 3835 (1)

5 out of 5
1 Customer Rating
5 Stars
100%
4 Stars
0%
3 Stars
0%
2 Stars
0%
1 Stars
0%

Have you used WM 3835?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Customer Images

Showing  1 - 1 的 1 review Showing All
Filter By:
Clear Filters X
  • Block Hbo1
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Cell Line/Tissue: mouse brain
    Verified Customer | Posted 11/15/2024
    We test Hbo1 inhibitor using HBO1 western blot. First lane is ctrl group. Lane 2 and 3 are WM 3835 injection groups.
    10mg/kg injection to mice for 10 days
    WM 3835 7366

There are no reviews that match your criteria.

Showing  1 - 1 的 1 review Showing All