Y-27632 in solution

Tocris Bioscience | Catalog # 7000

Sterile-filtered 10 mM solution of Y-27632, selective ROCK inhibitor, pre-dissolved in water
Tocris Bioscience

Key Product Details

Description

Sterile-filtered 10 mM solution of Y-27632, selective ROCK inhibitor, pre-dissolved in water
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Product Description

Y-27632 in solution is a convenient and ready-to-use 10 mM sterile-filtered solution of Y-27632 (Cat. No. 1254), pre-dissolved in water. Increases survival rate of human embryonic stem (hES) cells and iPSC undergoing cryopreservation. Optimizes naive human pluripotent stem cell growth and viability following naive cell derivation from primed ESCs and iPSCs using naive human stem cell medium (NHSM). Used as a component of growth media for urothelial organoids and in a protocol to generate brain organoids from human iPSCs.

Supplied in vials containing a minimum of 1 mL of Y-27632 solution.

Product Specifications for Y-27632 in solution

Molecular Weight

320.26

Formula

C14H21N3O.2HCl

Storage

Store at -20°C

Purity

≥97% (HPLC)

Chemical Name

trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride

CAS Number

129830-38-2

PubChem ID

9901617

InChI Key

IDDDVXIUIXWAGJ-LJDSMOQUSA-N

SMILES

N[C@H](C)[C@@]1([H])CC[C@H](C(NC2=CC=NC=C2)=O)CC1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble in water (supplied pre-dissolved at a concentration of 10mM)

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Product Documents for Y-27632 in solution

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Y-27632 in solution

For research use only

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  • test
    Name: Chi Ngo
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: iPSC-derived cardiomyocytes
    Verified Customer | Posted 08/13/2025
    Add Y-27632 to the final concentration of 10 uM to the recovering medium. Switch to the maintenance medium after 24h.
    To help with the viability of iPSC-derived cells after thaw.
    Y-27632 in solution 7000

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