ZM 226600

Tocris Bioscience | Catalog # 0882

Kir6 (KATP) channel opener
Tocris Bioscience
Discontinued Product
0882 has been discontinued. View all Inward Rectifier Potassium Channel Activators products.

Key Product Details

Description

Kir6 (KATP) channel opener
View all Inward Rectifier Potassium Channel Activators »

Product Description

ZM 226600 is a potent Kir6 (KATP) channel opener (EC50 = 0.5 μM), devoid of antiandrogen properties.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Product Specifications for ZM 226600

Molecular Weight

373.35

Formula

C16H14F3NO4S

Storage

Store at RT

Chemical Name

N-(4-Phenylsulfonylphenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide

CAS Number

147695-92-9

PubChem ID

5240098

InChI Key

LJLXQHHFAKVTNP-UHFFFAOYSA-N

SMILES

CC(O)(C(=O)NC1=CC=C(C=C1)S(=O)(=O)C1=CC=CC=C1)C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 37.34 100

Preparing Stock Solutions for ZM 226600

The following data is based on the product molecular weight 373.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.68 mL 13.39 mL 26.78 mL
5 mM 0.54 mL 2.68 mL 5.36 mL
10 mM 0.27 mL 1.34 mL 2.68 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for ZM 226600

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ZM 226600

For research use only

Related Research Areas

Ion Channels and Regulators

Customer Reviews for ZM 226600 (1)

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  • ZM 226600 was used to assess Kir2.2 channel opening
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 11/29/2018
    ZM 226600 was used to assess Kir2.2 channel opening.
    ZM 226600 0882

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