Zopiclone

Key Product Details

Product Description

A non benzodiazepine BZR agonist, with little difference in affinity for the BZ1 and BZ2 subtypes; however its CNS effects differ from those of other BZR ligands and this may be due to interaction with a different subunit.

Product Specifications for Zopiclone

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Zopiclone

The following data is based on the product molecular weight 388.81.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.75 mM	3.43 mL	17.15 mL	34.29 mL
3.75 mM	0.69 mL	3.43 mL	6.86 mL
7.5 mM	0.34 mL	1.71 mL	3.43 mL
37.5 mM	0.07 mL	0.34 mL	0.69 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.

• Im Potentiation of γ-aminobutyric acid induced chloride currents by various benzodiazepine site agonists with the α1γ2, β2γ2 and α1β2γ2 subtypes of cloned γ-aminobutyric acid type A receptors. Mol.Pharmacol. 1993 PMID: 7901754
• Munakata Heterogeneous distribution of benzodiazepine receptors among rat neostriatal neurones. Br.J.Pharmacol. 1996 PMID: 8762113
• Goa and Heel ZopiC.. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy as a hypnotic. Drugs 1986 PMID: 2874974

Product Documents for Zopiclone