Antibody Development & Validation in the Era of Spatial Proteomics Poster

Spatial proteomics enables researchers to map hundreds of proteins at subcellular resolution, providing deeper insight into tissue organization and disease mechanisms. But unlocking these insights requires antibodies that perform with exceptional sensitivity and specificity.

Bio-Techne antibody development and validation teams have developed and are continuously validating R&D Systems™ antibodies, including the Novus portfolio, for use on the COMET™ spatial biology platform from Lunaphore, a Bio‑Techne brand. This work combines antibody expertise with spatial biology capabilities to evaluate performance in multiplexed imaging workflows, including specificity, sensitivity, and compatibility across sequential staining cycles.

Poster Highlights:

• COMET™ Platform Advantages
• Expanded COMET Antibody Discovery Workflow
• Platform-specific antibody optimizations: concentration, elution efficiency, sensitivity and specificity
• Multiplex fluorescence images of immune checkpoint markers in Glioblastoma.