5-HT6 cDNA Clones

5-HT6 is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. It belongs to the G protein-coupled receptor 1 family. 5-HT6 is expressed in several human brain regions, most prominently in the caudate nucleus. The activity of 5-HT6 is mediated by G proteins that stimulate adenylate cyclase. 5-HT6 has a high affinity for tricyclic psychotropic drugs.