8 results for "CCL5/RANTES ELISA Kits" in 产品
CCL5/RANTES ELISA Kits
CCL5/RANTES is a secreted beta-chemokine that plays a primary role in the inflammatory immune response through chemoattraction and activation of leukocytes that express CCR1, 3, 4, or 5. The two N-terminal residues of CCL5 can be removed by CD26/DPPIV, generating a protein that functions as a chemotaxis inhibitor. The deposition of CCL5 on activated vascular endothelial cells is crucial for monocyte adhesion to damaged vasculature. CCL5 is upregulated in breast cancer and promotes tumor progression through the attraction of proinflammatory macrophages in addition to its actions on tumor cells, stromal cells, and the vasculature. In humans, CCR5 binding to CCL5 inhibits the infectivity of R5 (M-tropic) but not X4 (T-tropic) strains of HIV-1.
| Reactivity: | Monkey |
| Sensitivity: | 18.75 pg/mL |
| Assay Range: | 31.25 - 2000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Porcine |
| Sensitivity: | 1.15 ng/mL (example only; lot dependent) |
| Assay Range: | 3.125 - 200 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
| Reactivity: | Human |
| Sensitivity: | 6.6 pg/mL |
| Assay Range: | 31.2-2000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine) |
| Applications: | ELISA |
| Reactivity: | Mouse, Rat |
| Sensitivity: | 2 pg/mL |
| Assay Range: | 7.8-500 pg/mL (Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Citrate Plasma) |
| Applications: | ELISA |
| Reactivity: | Human |
| Assay Range: | 15.6-1000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Assay Range: | 31.2-2000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Canine |
| Assay Range: | 23.4-1500 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Sensitivity: | 0.78 pg/mll (example only; lot dependent) |
| Assay Range: | 0.78-50 pg/ml (example only; lot dependent) |
| Applications: | ELISA |
