179 results for "Jak2" in 产品
Jak2 Products
Jak1, Jak 2, and Jak3 belong to the Janus Kinases family of protein tyrosine kinases that couple to cytokine receptors once activated by their corresponding ligands. Activation of Jak family members occurs via phosphorylation at two adjacent tyrosine residues as well as potentially one or more serine residues. Jaks activate members of the STAT family of transcription factors by phosphorylating critical tyrosine regulatory sites.
Jak1 is required for the activation of STAT1 and STAT2 in ...
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #53B7 |
| Applications: | WB, ELISA, Flow, ICC/IF, Simple Western, + 1 More |
![Western Blot: Jak2 Antibody (53B7)BSA Free [NBP2-59451]](https://resources.rndsystems.com/images/products/Jak2-Antibody-53B7-Western-Blot-NBP2-59451-img0004.jpg "Western Blot: Jak2 Antibody (53B7)BSA Free [NBP2-59451]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #6-D3 |
| Applications: | IHC, WB, Flow, ICC/IF, MA |
![Western Blot: Jak2 Antibody (6-D3) [NBP2-66913]](https://resources.rndsystems.com/images/products/Jak2-Antibody-6-D3-Western-Blot-NBP2-66913-img0003.jpg "Western Blot: Jak2 Antibody (6-D3) [NBP2-66913]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SY24-03 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1129 |
| Applications: | IHC, WB, Flow, ICC/IF, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![Western Blot: Jak2 Antibody [NBP1-22975]](https://resources.rndsystems.com/images/products/Jak2-Antibody-Western-Blot-NBP1-22975-img0004.jpg "Western Blot: Jak2 Antibody [NBP1-22975]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1A4 |
| Applications: | IHC, WB, ELISA, IP |
![Jak2 [p Tyr1007, p Tyr1008] Antibody (1A4)](https://resources.rndsystems.com/images/products/nbp3-26415_rabbit-jak2-p-tyr-1007-p-tyr-1008-mab-1a4-262202413221522.jpg "Immunoprecipitation: Jak2 [p Tyr1007, p Tyr1008] Antibody (1A4) [NBP3-26415] -")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: Jak2 AntibodyBSA Free [NBP2-41310]](https://resources.rndsystems.com/images/products/Jak2-Antibody-Western-Blot-NBP2-41310-img0001.jpg "Western Blot: Jak2 AntibodyBSA Free [NBP2-41310]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: Jak2 Antibody [NBP2-55362]](https://resources.rndsystems.com/images/products/Jak2-Antibody-Western-Blot-NBP2-55362-img0002.jpg "Western Blot: Jak2 Antibody [NBP2-55362]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI7D12 |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Jak2 Antibody (OTI7D12) [NBP2-45468]](https://resources.rndsystems.com/images/products/Jak2-Antibody-7D12-Immunohistochemistry-NBP2-45468-img0001.jpg "Immunohistochemistry-Paraffin: Jak2 Antibody (OTI7D12) [NBP2-45468]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI7D12 |
| Applications: | IHC |
![Immunohistochemistry: Jak2 Antibody (OTI7D12) - Azide and BSA Free [NBP2-71056]](https://resources.rndsystems.com/images/products/Jak2-Antibody-OTI7D12-Azide-and-BSA-Free-Immunohistochemistry-NBP2-71056-img0001.jpg "Immunohistochemistry: Jak2 Antibody (OTI7D12) - Azide and BSA Free [NBP2-71056]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Jak2 [p Tyr1007, p Tyr1008] Antibody [NBP3-13138]](https://resources.rndsystems.com/images/products/Jak2-[p-Tyr1007--p-Tyr1008]-Antibody-Western-Blot-NBP3-13138-img0002.jpg "Western Blot: Jak2 [p Tyr1007, p Tyr1008] Antibody [NBP3-13138]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #4B0K1 |
| Applications: | WB |
![Immunoprecipitation: Jak2 Antibody (4B0K1) [NBP3-15825]](https://resources.rndsystems.com/images/products/Jak2-Antibody-4B0K1-Immunoprecipitation-NBP3-15825-img0002.jpg "Immunoprecipitation: Jak2 Antibody (4B0K1) [NBP3-15825]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Jak2 Antibody [NBP2-38476]](https://resources.rndsystems.com/images/products/Jak2-Antibody-Immunohistochemistry-NBP2-38476-img0001.jpg "Immunohistochemistry-Paraffin: Jak2 Antibody [NBP2-38476]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #10B6 |
| Applications: | ELISA, ICC/IF |
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human Jak2 His Protein [NBP2-23154]](https://resources.rndsystems.com/images/products/Recombinant-Human-Jak2-Protein-SDS-Page-NBP2-23154-img0002.jpg "SDS-PAGE: Recombinant Human Jak2 His Protein [NBP2-23154]")
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
Potent, selective inhibitor of MEK1 and 2
| Chemical Name: | 1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene |
Potent JAK inhibitor
| Alternate Names: | Tofacitinib citrate |
| Chemical Name: | (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile citrate |
| Purity: | ≥98% |
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
| Alternate Names: | Tyrphostin AG 490 |
| Chemical Name: | (E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide |
| Purity: | ≥98% |
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
| Alternate Names: | CEP-701 |
| Chemical Name: | (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one |
| Purity: | ≥98% |
Potent and selective JAK1/JAK2 inhibitor; orally bioavailable
| Alternate Names: | INCB018424 |
| Chemical Name: | (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile |
| Purity: | ≥98% |
JAK2/STAT3 signaling pathway inhibitor
| Chemical Name: | (1R,5R,6R,7S)-rel-4-Oxo-8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid 6,7-dimethyl ester |
| Purity: | ≥98% |
Highly potent JAK1 and JAK2 inhibitor; also inhibits JAK3 and Tyk2
| Alternate Names: | INCB 28050 |
| Chemical Name: | 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile |
| Purity: | ≥98% |
