Activin AB Products

Activins and Inhibins are TGF‑beta superfamily proteins that regulate a wide range of processes including mesoderm induction, reproductive system development and function, liver growth and regeneration, wound healing, and inflammation. Activins signal through heterodimeric receptor complexes composed of type I (Activin RIA or RIB) and type II (Activin RIIA or RIIB) transmembrane Ser/Thr kinases. Activin A, B, and AB are expressed in gonadal tissues as biologically active proteins. Activin A and B likely do not compensate for one another or have overlapping functions.