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2 results for "ARK5/NUAK1 Small Molecules and Peptides" in 产品
ARK5/NUAK1 Small Molecules and Peptides
AMPK-related kinase 5 (ARK5), also known as NUAK1, is a 74 kDa intracellular Ser/Thr kinase that promotes cell survival during nutrient deprivation and TNF family ligand-induced apoptosis. ARK5 is activated by Akt, NDR2, and LKB1-mediated phosphorylation at multiple serine and threonine residues. It inhibits the activation of Caspase-6, Caspase-8, ...
Potent and selective NUAK1/2 inhibitor
| Chemical Name: | N-3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]propanamide |
| Purity: | ≥98% |
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Potent and selective NUAK1 inhibitor
| Chemical Name: | 5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one |
| Purity: | ≥98% |
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