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1 result for "BAK Small Molecules and Peptides" in 产品
BAK Small Molecules and Peptides
Bcl-2-antagonist/killer (BAK), also known as BAK1 and Bcl-2-like Protein 7, is a proaptoptotic member of the Bcl-2 protein family with a predicted molecular weight of approximately 23 kDa. It contains four Bcl-2 homology domains, BH1-BH4, and a C-terminal transmembrane domain. Human BAK shares 77% amino acid sequence identity with the mouse and rat orthologs. BAK primarily localizes to the outer mitochondrial membrane where it is redundantly required, along with Bax, for the release of ...
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines
| Chemical Name: | 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide |
| Purity: | ≥98% |
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