2 results for "BCR Small Molecules and Peptides" in 产品

BCR Small Molecules and Peptides

BCR (Breakpoint cluster region protein) is a novel 155-165 kDa Ser/Thr protein kinase. It is found in fibroblasts and hematopoietic cells, interacts with 14-3-3, and serves as a natural inhibitor of the growth factor-associated c-Abl nonreceptor protein tyrosine kinase. Human BCR is 1271 amino acids (aa) in length. It contains a coiled-coil dimeriz...

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Selective allosteric inhibitor of Bcr-Abl; analog of GNF 2 (Cat. No. 4399)

Chemical Name: N-(2-Hydroxyethyl)-3-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]benzamide
Purity: ≥98%
Selective allosteric inhibitor of Bcr-Abl; analog of GNF 2 (Cat. No. 4399)
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Potent multi-kinase and pan-Bcr-Abl inhibitor

Alternate Names: Ponatinib
Chemical Name: 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide
Purity: ≥98%
Potent multi-kinase and pan-Bcr-Abl inhibitor
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