3 results for "Caspase-1 Small Molecules and Peptides" in 产品
Caspase-1 Small Molecules and Peptides
Caspase-1, also known as IL-1 beta-converting enzyme (ICE), is an aspartic protease that plays a key role in the inflammatory response and apoptosis. Caspase-1 precursor (about 50kDa) can be cleaved and the active enzyme consists of a complex of two 20 kDa and two 10 kDa subunits which associate following cleavage of inactive precursors. Caspase-1 ...
| Reactivity: | Multi-Species |
| Applications: |
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High affinity and selective caspase-4 and caspase 1/ICE inhibitor; orally bioavailable
| Alternate Names: | Belnacasan |
| Chemical Name: | N-(4-Amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-L-prolinamide |
| Purity: | ≥98% |
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Potent and selective inhibitor of caspases 1, 5 and 4
| Purity: | ≥95% |
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