Caspase-13: Products
Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. They are expressed as latent zymogens and are activated by an autoproteolytic mechanism or by processing by other proteases (frequently other caspases). Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7).
Caspases are regulated by a variety of stimili, including APAF1, CFLAR/FLIP, NOL3/ARC, and members of the inhibitor of apoptosis (IAP) family such as BIRC1/NAIP, BIRC2/cIAP-1, BIRC3/cIAP-2, BIRC4/XIAP, BIRC5/Survivin, and BIRC7/Livin. IAP activity is modulated by DIABLO/SMAC or PRSS25/HTRA2/Omi. Cell-permeable and irreversible peptide inhibitors are also available for different caspases.
Multi Brand Search Results for "Caspase-13"
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Bio-Techne BrandProduct Category
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Novus Biologicals provides the life science community with high-performing antibodies to over 20,000 unique targets. These antibodies are available conjugated to multiple fluorophores and tested in numerous assays and species. read more
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Tocris Bioscience is the leading supplier of novel, exclusive small molecules and peptides for life science research. read more
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ProteinSimple develops and manufactures proprietary, fully automated systems for protein analysis. read more