7 results for "Caspase-3 Small Molecules and Peptides" in 产品
Caspase-3 Small Molecules and Peptides
Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin. Normally, it is an inactive, exclusively cytosolic homodimer....
| Reactivity: | Multi-Species |
| Applications: |
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Caspase-3 Inhibitor
| Purity: | ≥95% |
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Potent pro-apoptotic anticancer agent; activates caspase-3
| Alternate Names: | CDDP |
| Chemical Name: | cis-Diaminodichloroplatinum |
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Selective IGF1R inhibitor
| Alternate Names: | Picropodophyllin |
| Chemical Name: | (5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one |
| Purity: | ≥97% |
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Selective cyclooxygenase-2 (COX-2) inhibitor
| Alternate Names: | SC 58635,Celebrex |
| Chemical Name: | 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide |
| Purity: | ≥98% |
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Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
| Chemical Name: | 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione |
| Purity: | ≥98% |
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Activator of procaspase-3; pro-apoptotic
| Chemical Name: | 4-(Phenylmethyl)-1-piperazineacetic acid [[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide |
| Purity: | ≥98% |
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