4 results for "Cdc2-like Kinase Inhibitors Small Molecules and Peptides" in 产品
Cdc2-like Kinase Inhibitors Small Molecules and Peptides
The CLK (Cdc2-like kinase) family has four family members: CLK1/STY, CLK2, CLK3 and CLK4. CLKs are dual specificity protein kinases which are self-activated through autophosphorylation on tyrosine residues and phosphorylate their substrates on serine and threonine residues. All family members have N-terminal domains which are rich in serine and arginine residues. They also have a conserved EHLAMMERRIG sequence in the catalytic domain and are thus also known as LAMMER kinases.
Mammalian CLK ...
Potent inhibitor of Clk-family kinases; also inhibits DYRK1A/B
| Chemical Name: | (1Z)-1-(3-Ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone |
| Purity: | ≥98% |
Inhibitor of Clk and DYRK kinases
| Chemical Name: | 5-(1,3-Benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]-4-pyrimidinamine hydrochloride |
| Purity: | ≥98% |
Potent LMTK3 inhibitor
| Chemical Name: | 6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine |
| Purity: | ≥98% |
Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B
| Chemical Name: | 4-[1,1-Dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]benzamide |
| Purity: | ≥98% |
