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5 results for "CFTR Small Molecules and Peptides" in 产品
CFTR Small Molecules and Peptides
Cystic fibrosis transmembrane conductance regulator (CFTR) is a multi-pass transmembrane protein that functions as a chloride channel. CFTR belongs to the ATP-binding cassette (ABC) superfamily. Mutations in CFTR cause the pulmonary disease, cystic fibrosis (CF). Specifically, deletion of phenyalanine at position 508 (DeltaF508-CFTR) results in a f...
Voltage-independent, selective CFTR chloride channel blocker
| Chemical Name: | 4-[[4-Oxo-2-thioxo-3-[3-trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]benzoic acid |
| Purity: | ≥98% |
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Reversible, voltage-dependent CFTR chloride channel blocker
| Chemical Name: | N-2-Naphthalenyl-2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]glycine hydrazide |
| Purity: | ≥97% |
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Potent and selective CFTR potentiator
| Chemical Name: | N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide |
| Purity: | ≥98% |
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Activates Cl- conductance and hKCa3.1 channels
| Chemical Name: | 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one |
| Purity: | ≥99% |
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Inhibits calcium-sensitive chloride currents
| Chemical Name: | 5-Nitro-2-(3-phenylpropylamino)benzoic acid |
| Purity: | ≥98% |
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