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1 result for "Chk2 Small Molecules and Peptides" in 产品
Chk2 Small Molecules and Peptides
The Chk2 checkpoint kinase is an integral member of the signaling cascade that controls cell cycle checkpoints. In response to genotoxic insults Chk2 is phosphorylated by ATM or ATM-related kinases. Phosphorylation of Chk2 T68 promotes the formation of Chk2 oligomers. Oligomerization is a critical event in the activation of the Chk2 kinase as i...
Potent and selective allosteric inhibitor of Wip1 phosphatase
| Chemical Name: | 5-[[(5-Chloro-2-methyl-3-pyridinyl)amino]methyl]-N-[(1S)-1-(cyclopentylmethyl)-2-(cycloprpylamino)-2-oxoethyl]-2-thiophenecarboxamide |
| Purity: | ≥98% |
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