15 results for "Compounds for HSC Proliferation and Renewal" in 产品
Compounds for HSC Proliferation and Renewal
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
| Chemical Name: | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity: | ≥99% |
Highly selective GSK-3 inhibitor; acts as Wnt activator
| Alternate Names: | CHIR99021,CT99021 |
| Chemical Name: | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity: | ≥98% |
Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin
| Alternate Names: | PGE2 |
| Chemical Name: | (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1oic acid |
| Purity: | ≥98% |
Selective inhibitor of p38 MAPK
| Chemical Name: | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine |
| Purity: | ≥98% |
Potent GSK-3 inhibitor; also inhibits cdks
| Alternate Names: | 6BIO |
| Chemical Name: | (2'Z,3'E)-6-Bromoindirubin-3'-oxime |
| Purity: | ≥98% |
Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development
| Chemical Name: | (5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxo-prosta-5,13-dien-1oic acid |
| Purity: | ≥95% |
Potent integrin inhibitor (αvβ3/αvβ6); also improves stem cell attachment in 3D cell culture scaffolds
| Purity: | ≥95% |
Glutathione (GSH) precursor; neuroprotective
| Chemical Name: | (2R)-2-(Acetylamino)-3-mercaptopropanamide |
High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
| Chemical Name: | 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine |
| Purity: | ≥98% |
Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO
| Chemical Name: | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity: | ≥97% |
Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment
| Chemical Name: | 4-[2-[[2-Benzo[b]thien-3-yl-9-(1-methylethyl)-9H-purin-6-yl]amino]ethyl]phenol |
| Purity: | ≥98% |
Dipeptidyl peptidase IV (DPP-IV) inhibitor
| Alternate Names: | Ile-Pro-Ile |
| Chemical Name: | L-Isoleucyl-L-prolyl-L-isoleucine |
| Purity: | ≥98% |
Potent aryl hydrocarbon receptor (AhR) antagonist
| Chemical Name: | 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide |
| Purity: | ≥98% |
PARP-1 inhibitor
| Chemical Name: | Pyridine-3-carboxamide |
| Purity: | ≥99% |
BET bromodomain inhibitor; arrests cell cycle at G1 phase
| Alternate Names: | TEN 010 |
| Chemical Name: | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity: | ≥98% |
