Cyclo(-RGDfK)

Tocris Bioscience | Catalog # 8917

Potent integrin inhibitor (αvβ3/αvβ6); also improves stem cell attachment in 3D cell culture scaffolds
Tocris Bioscience

Key Product Details

Description

Potent integrin inhibitor (αvβ3/αvβ6); also improves stem cell attachment in 3D cell culture scaffolds
View all Cell Adhesion Inhibitors »

Product Description

Cyclo(-RGDfK) is a cyclic peptide, potent integrin inhibitor (IC50 values are 2.3 and 55 nM for αvβ3 and αvβ6, respectively). Cyclo(-RGDfK) improves human pluripotent stem cell (hPSC) adhesion and proliferaton on 3D cell culture synthetic surfaces. Can also be used to target fluorophores and cargo to cancer cells as αvβ3 integrin is upregulated on cancer cells.

Product Specifications for Cyclo(-RGDfK)

Molecular Weight

603.68

Formula

C27H41N9O7

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

161552-03-0

PubChem ID

10196873

InChI Key

NVHPXYIRNJFKTE-HAGHYFMRSA-N

SMILES

O=C(NCC(N[C@@H](CC(O)=O)C(N[C@H](CC1=CC=CC=C1)C(N[C@H]2CCCCN)=O)=O)=O)[C@H](CCCNC(N)=N)NC2=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

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Product Documents for Cyclo(-RGDfK)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Cyclo(-RGDfK)

For research use only

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