CRHBP Proteins and Enzymes

CRHBP (Corticotrophin-releasing Hormone-Binding Protein) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. The molecule is approximately 300 amino acids in length and demonstrates five intrachain disulfide bonds. Species differences exist; human CRHBP is found in plasma while rodent and sheep CRH...