8 results for "Cytochrome P450 Inhibitors" in 产品
Cytochrome P450 Inhibitors
Cytochrome P450 (CYP450) enzymes are a diverse group of catalysts that contains 57 members in humans. CYPs are usually membrane-bound and are localized to the inner mitochondrial or endoplasmic reticular membrane. CYPs have oxygenase activity and commonly catalyze redox reactions, involving the oxidation of the substrate and reduction of water. This group of enzymes contain a heme iron within the active site, which is essential for catalytic activity.
CYPs have been found in all organisms ...
Cytochrome P450c17 inhibitor
| Chemical Name: | cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl] methoxy]phenyl]piperazine |
| Purity: | ≥98% |
11-β hydroxylase inhibitor
| Chemical Name: | 2-Methyl-1,2-di-3-pyridinyl-1-propanone |
| Purity: | ≥98% |
Potent, reversible non-steroidal aromatase inhibitor
| Alternate Names: | CGS 20267 |
| Chemical Name: | 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile |
| Purity: | ≥98% |
Blocks retinoic acid metabolism
| Alternate Names: | R-75251 |
| Chemical Name: | 5-[(3-Chlorophenyl)-1H-imidazol-1-ylmethyl]-1H-benzimidazole dihydrochloride |
| Purity: | ≥98% |
Cytochrome P450 inhibitor; antifungal
| Alternate Names: | CLT |
| Chemical Name: | 1-(2-Chloro-α,α-diphenylbenzyl)imidazole |
| Purity: | ≥98% |
CYP17 inhibitor; also androgen receptor antagonist
| Alternate Names: | TOK-001,VN/124-1 |
| Chemical Name: | (3β)-17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3-ol |
| Purity: | ≥98% |
Allosteric Calcium-sensing receptor (CaSR) agonist; also CYP2D2 inhibitor and Ca2+ channel blocker; orally bioavailable
| Alternate Names: | AMG 073 |
| Chemical Name: | N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine hydrochloride |
| Purity: | ≥98% |
Potent CYP17A1 inhibitor
| Chemical Name: | (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-yl acetate |
| Purity: | ≥98% |
