DCTN5 Proteins and Enzymes

Dynactin (see MIM 601143) is a multimeric protein essential for minus-end-directed transport driven by themicrotubule-based motor dynein (see DYNC1H1; MIM 600112). DCTN5 is a subunit of the pointed-end subcomplex of dynactinthat is thought to interact with membranous cargo (Parisi et al., 2004 (PubMed 15043994)).(supplied by OMIM)