6 results for "DEK" in 产品

DEK Products

The DEK oncogene is an approximately 45 kDa phosphoprotein with pleiotropic activities. It is a chromatin remodeling factor, a transcriptional coactivator and corepressor, a component of RNA spliceosomes, and a promoter of DNA repair during apoptosis. DEK is upregulated in many cancers and promotes epithelial cell transformation. It functions as a proinflammatory factor when secreted by activated macrophages. It is an autoantigen in juvenile arthritis and lupus and a target of chromosomal translocation with the CAN gene in acute myelogenous leukemia. DEK contains one SAP domain (aa 149-183), one nuclear localization sequence (aa 205-221), and a DNA-binding C-terminal domain (aa 321-375).

Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #715511
Applications: IHC, ICC/IF
DEK antibody in HeLa Human Cell Line by Immunocytochemistry (ICC).
(2)
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Western Blot: DEK Antibody [NBP2-38834]
(7)
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Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #715524
Applications: IHC, WB
Detection of Human DEK antibody by Western Blot.
(2)
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC
Immunohistochemistry-Paraffin: DEK Antibody [NBP2-49135]
(4)
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB, ICC/IF, IP
Western Blot: DEK Antibody [NBP2-98888]
(3)
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: ICC/IF
DEK Antibody - BSA Free
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