3 results for "Dopamine D1 and D5 Receptor Antagonists" in 产品

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Dopamine D1 and D5 Receptor Antagonists

D1 and D5 receptors (also known as D1-like receptors) are a subset of the dopamine receptor G-protein-coupled receptor family that also includes D2, D3 and D4. The two receptor subtypes are highly homologous and very few ligands have been identified that are selective between the D1 and D5 subtypes. D1 receptors are widely expressed throughout the brain, whereas D5 receptors show a restricted distribution (mainly limbic areas).

SCH 23390 hydrochloride

Catalog #: 0925
(3)
Citations (141)
Product Documents

Selective D1-like antagonist; also 5-HT2C agonist and Kir3 channel blocker

Alternate Names: (R)-(+)-SCH 23390 hydrochloride
Chemical Name: (R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
Purity: ≥98%
Selective D1-like antagonist; also 5-HT2C agonist and Kir3 channel blocker

SKF 83566 hydrobromide

Catalog #: 1586
Citations (12)
Product Documents

Potent and selective D1-like antagonist; also inhibits adenylyl cyclase 2

Chemical Name: 8-Bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrobromide
Purity: ≥98%
Potent and selective D1-like antagonist; also inhibits adenylyl cyclase 2

SCH 39166 hydrobromide

Catalog #: 2299
Citations (18)
Product Documents

High affinity D1-like antagonist

Alternate Names: Ecopipam hydrobromide
Chemical Name: (6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol hydrobromide
Purity: ≥98%
High affinity D1-like antagonist
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