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Dopamine D2 R/DRD2 Fluorescent Probes and Dyes

DRD2 encodes the D2 subtype of the dopamine receptor that inhibits adenylyl cyclase activity. Alternative splicing of this G protein-coupled receptor results in two transcript variants encoding different isoforms. DRD2 plays a major role in the neural circuitry that mediates behavioral control, an ability that is essential for adaptive responding and is compromised in a variety of common neuropsychiatric disorders.

Potent and partially selective hD2 dopamine receptor fluorescent antagonist

Purity: ≥95%
Application of CELT-426 (100 nM) in CHO cells.
(3)
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