84 results for "ERK5/BMK1" in 产品
ERK5/BMK1 Products
ERK1 and ERK2 (also known as MAPK3 and MAPK1) are 44 and 42 kDa Ser/Thr kinases, respectively. They are part of the Ras-Raf-ERK signal transduction cascade often found downstream of growth factor receptor activation. ERK1 and ERK2 were initially isolated and cloned as kinases activated in response to insulin and NGF. They are expressed in most, if not all, mammalian tissues. Dual threonine and tyrosine phosphorylation activate both ERKs, at Thr202/Tyr204 for human ERK1 and Thr185/Tyr187 for ...
Non-selective protein kinase inhibitor
| Alternate Names: | AM-2282 |
| Chemical Name: | [9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: ERK5/BMK1 Antibody [NBP1-42673]](https://resources.rndsystems.com/images/products/ERK5-BMK1-Antibody-Western-Blot-NBP1-42673-img0002.jpg "Western Blot: ERK5/BMK1 Antibody [NBP1-42673]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3H2 |
| Applications: | WB, Flow, ICC/IF, CyTOF-ready |
![Western Blot: ERK5/BMK1 Antibody (OTI3H2)Azide and BSA Free [NBP2-71243]](https://resources.rndsystems.com/images/products/ERK5-BMK1-Antibody-OTI3H2-Azide-and-BSA-Free-Western-Blot-NBP2-71243-img0002.jpg "Western Blot: ERK5/BMK1 Antibody (OTI3H2)Azide and BSA Free [NBP2-71243]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3H2 |
| Applications: | WB, Flow, ICC/IF |
ERK5/BMK1 inhibitor; also BRD4 inhibitor
| Chemical Name: | 2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
| Purity: | ≥98% |
Selective MEK5 and ERK5 inhibitor
| Chemical Name: | (3Z)-3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-N,N-dimethyl-2-oxo-1H-indole-6-carboxamide |
| Purity: | ≥98% |
Potent and selective ERK5 inhibitor
| Chemical Name: | 5,11-Dihydro-2-[[2-ethoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5-methyl,11-(methylsulfonyl)-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #5C1P5 |
| Applications: | IHC, WB |
![Western Blot: ERK5/BMK1 Antibody (5C1P5) [NBP3-16298]](https://resources.rndsystems.com/images/products/ERK5-BMK1-Antibody-5C1P5-Western-Blot-NBP3-16298-img0004.jpg "Western Blot: ERK5/BMK1 Antibody (5C1P5) [NBP3-16298]")
Potent and selective ERK5 Degrader (PROTAC®)
| Chemical Name: | (2S,4R)-1-((S)-2-(7-(4-(4-((5,11-Dimethyl-6-oxo-6,11-dihydro-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-2-yl)amino)-3-methoxyphenyl)piperazin-1-yl)heptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: ERK5/BMK1 Antibody [NBP3-10647]](https://resources.rndsystems.com/images/products/ERK5-BMK1-Antibody-Immunohistochemistry-Paraffin-NBP3-10647-img0001.jpg "Immunohistochemistry-Paraffin: ERK5/BMK1 Antibody [NBP3-10647]")
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: ERK5/BMK1 Antibody [NBP2-58369]](https://resources.rndsystems.com/images/products/ERK5-BMK1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-58369-img0001.jpg "Immunocytochemistry/ Immunofluorescence: ERK5/BMK1 Antibody [NBP2-58369]")
| Reactivity: | Human |
| Applications: | WB |
![Western Blot: ERK5/BMK1 Overexpression Lysate [NBL1-12879]](https://resources.rndsystems.com/images/products/ERK5-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12879-img0002.jpg "Western Blot: ERK5/BMK1 Overexpression Lysate [NBL1-12879]")
| Reactivity: | Human |
| Applications: | WB |
![Western Blot: ERK5/BMK1 Overexpression Lysate [NBL1-12882]](https://resources.rndsystems.com/images/products/ERK5-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12882-img0002.jpg "Western Blot: ERK5/BMK1 Overexpression Lysate [NBL1-12882]")
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
![ERK5/BMK1 Antibody [CoraFluor™ 1]](https://resources.rndsystems.com/images/products/af2848cl1_goat-erk5-bmk1-pab-corafluor-1-10920251443120.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
