FBXO16 Proteins and Enzymes

The FBXO15 gene encodes a f-box only protein 16 that in isoform 1 is 292 amino acids long and 34 kDA and in isoform 2 is 280 amino acids long at 33 kDA. This protein is thought to recognize as well as bind to various phosphorylated proteins in encouraging their ubiquination and degradation. FBXO15 interacts with genes SKP1 and UBC and is associated to anemia and cholangiocarcinoma.