5 results for "G9a/GLP Inhibitor Small Molecules and Peptides" in 产品

G9a/GLP Inhibitor Small Molecules and Peptides

G9a and GLP (G9a like protein) are histone lysine methyltransferases, also known as euchromatic histone-lysine n-methyltransferase 2 (EMHT2) and EMHT1 respectively. They exist in heteromeric complexes in vivo and lead to transcriptional repression through methylation of H3K9.

G9a or GLP knockout mice exhibit severe retardation during embryonic growth and early lethality, showing G9a/GLP H3K9 methylation is required for embryonic development. Upregulation of G9a/GLP expression is found in ...

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GLP and G9a inhibitor

Chemical Name: 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride
Purity: ≥98%
GLP and G9a inhibitor
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Potent G9a and GLP inhibitor

Chemical Name: 7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine
Purity: ≥98%
Potent G9a and GLP inhibitor
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Selective G9a and GLP inhibitor

Chemical Name: 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine
Purity: ≥98%
Selective G9a and GLP inhibitor
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Potent and selective G9a and GLP inhibitor

Chemical Name: 2-(4,4-Difluoro-1-piperidinyl)-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine
Purity: ≥98%
Potent and selective G9a and GLP inhibitor
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Potent and selective G9a/GLP inhibitor

Chemical Name: 5'-Methoxy-6'-[3-(1-pyrrolidinyl)propoxy]spiro[cyclobutane-1,3'-[3H]indol]-2'-amine
Purity: ≥98%
Potent and selective G9a/GLP inhibitor
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