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GABA-A Receptor Agonists

GABAA Receptor Subunits

The majority of human endogenous GABAA receptors are composed of α1-, β2- and γ2-subunits in a 2:2:1 ratio (α2β2γ), however the exact subunit conformation is determined by the expression of different subunits in a given cell type. Some subunits are only expressed in specific brain areas, for example receptors containing the α2-subunit are found in regions where the α1-subunit is absent or expressed at low levels, such as the ...

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GABAA partial agonist; acts at benzodiazepine site

Chemical Name: 2',4-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]-pyridin-3-yl]-[1,1'-biphenyl]-2-carbonitrile
Purity: ≥98%
GABAA partial agonist; acts at benzodiazepine site
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