8 results for "GABA-B Receptor Antagonists Small Molecules and Peptides" in 产品
GABA-B Receptor Antagonists Small Molecules and Peptides
GABAB receptors are GPCRs composed of seven transmembrane domains and a large extracellular N-terminal, and are responsible for mediating the inhibitory effects of GABA, alongside ionotropic GABAA and GABAA-ρ receptors. They are composed of 850 - 960 amino acids, and are most similar in structure to metabotropic glutamate receptors (mGluRs).
These receptors are heterodimers of GABAB1 and GABAB2 subunits. The GABAB1 subunit hosts the binding site for GABA and other ligands, while the GABAB2...
Potent and selective GABAB antagonist
| Chemical Name: | (2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinic acid hydrochloride |
| Purity: | ≥98% |
Potent and selective GABAB antagonist
| Chemical Name: | [S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl) phosphinic acid |
| Purity: | ≥96% |
Selective GABAB antagonist
| Chemical Name: | (RS)-3-Amino-2-(4-chlorophenyl)propylsulfonic acid |
| Purity: | ≥98% |
Selective GABAB antagonist; more potent than Saclofen (Cat. No. 0246)
| Chemical Name: | (RS)-3-Amino-2-(4-chlorophenyl)-2-hydroxypropyl-sulfonic acid |
Selective and competitive GABAB antagonist; orally bioavailable
| Chemical Name: | (2S)-(+)-5,5-Dimethyl-2-morpholineacetic acid |
| Purity: | ≥98% |
Selective GABAB antagonist; brain penetrant
| Chemical Name: | (3-Aminopropyl)(diethoxymethyl)phosphinic acid |
Potent and selective GABAB antagonist
| Chemical Name: | 3-[[(3,4-Dichlorophenyl)methyl]amino]propyl] diethoxymethyl)phosphinic acid |
| Purity: | ≥98% |
GABAB antagonist; displays activity at presynaptic receptors
| Chemical Name: | (3-Aminopropyl)ethylphosphinic acid hydrochloride |
| Purity: | ≥98% |
