Having trouble trying to find the right product? Chat with our scientists below - we're here to help!
2 results for "gamma-Secretase Modulators" in 产品
gamma-Secretase Modulators
γ-secretase is a multi-subunit internal protease that cleaves within the transmembrane domain of its substrates. It is an integral membrane protein and minimally consists of four proteins; presenilin, nicastrin, APH-1 and PEN-2. Presenilin is an aspartic protease and the catalytic subunit of the complex.
γ-secretase is involved in the processing of Notch. The Notch receptor is a single transmembrane spanning protein involved in angiogenesis and cell differentiation during embryonic ...
γ-secretase modulator; Notch-sparing
| Chemical Name: | (3E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-2-piperidone |
| Purity: | ≥98% |
Loading...
γ-secretase pseudo-inhibitor
| Chemical Name: | (2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide |
| Purity: | ≥98% |
Loading...