GDF-3 Lysates

GDF-3 (Growth Differentiation Factor-3; Vgr-2) is a TGF-beta superfamily member that is expressed in undifferentiated embryonic stem (ES) cells, white adipose tissue, and the brain. GDF-3 is upregulated in adipocytes by a high fat diet, promoting adipogenesis and obesity. Both proGDF-3 and mature GDF-3 lacking the propeptide can oppose BMP activity...