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3 results for "GLP-1R" in 产品
GLP-1R Products
GLP-1 R (Glucagon-like Peptide 1 Receptor) is a class B, G protein-linked, seven transmembrane domain protein that is expressed in pancreas, lung, heart, kidney, hypothalamus, and stomach. It is a receptor for Glucagon-like Peptide, a regulator of insulin secretion by pancreatic beta cells. Drugs that target GLP-1 R are of great interest for diabetes related research. Known agonists for GLP-1 R include GLP-1, Boc5, and Cpd1. Following experiments in mouse models, GLP-1 R agonists may also useful in the treatment of acute myocardial infarction.
Potent GLP-1 receptor antagonist
| Purity: | ≥95% |
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Metabolite of GLP-1-(7-36) (Cat. No. 2082)
| Alternate Names: | Glucagon-like peptide 1 (9-36) amide |
| Purity: | ≥95% |
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Non-competitive GLP-1 antagonist; orally bioavailable and brain penetrant
| Chemical Name: | 7-(4-Chlorophenyl)-5,8-dihydro-1,3-dimethyl-5,5-bis(trifluoromethyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione |
| Purity: | ≥98% |
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