5 results for "Glycine Receptor Agonists Small Molecules and Peptides" in 产品

Glycine Receptor Agonists Small Molecules and Peptides

Glycine receptors (GlyR) are members of the cys-loop family of ligand-gated ion channels, responsible for mediating the inhibitory effects of glycine. They are widely distributed throughout the CNS, particularly within the hippocampus, spinal cord and brain stem.

Glycine receptors exist as pentameric proteins, homo-oligomers of the α isoforms (α1, α2, α3 or α4) or hetero-oligomers which also contain the β-subtype variant (β1) which is essential for targeting ...

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Endogenous potentiator of NMDA receptors

Chemical Name: Aminoethanoic acid
Endogenous potentiator of NMDA receptors
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Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant

Chemical Name: 2-Propoxy-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate
Purity: ≥98%
Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant
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Non-selective endogenous glycine receptor agonist

Chemical Name: 2-Aminoethylsulfinic acid
Non-selective endogenous glycine receptor agonist
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PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist

Chemical Name: 5-Methyl-5,8,9,10,11a,12-hexahydro-4H-8,11-ethanopyrido[3',2':3,4]diazepino[6,7,1-hi]indole hydrochloride
Purity: ≥98%
PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
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PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist

Chemical Name: N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate
Purity: ≥98%
PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
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